21 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic #differential ... #Diagnosis #Management ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Diagnosis Framework ... (>1000): • DILI ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Induced Liver Injury ... Diagnosis Algorithm ... disease, Hepatic ischaemia ... #Diagnosis #Algorithm ... #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... normal - Hemolysis, NASH ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Generalized Algorithm for the Evaluation of Dermatologic Processes - Branches: Erythroderma Petechial Fluid-Filled Maculopapular 

#Diagnosis #Dermatology
Generalized Algorithm ... Maculopapular #Diagnosis ... #Dermatology #Rash ... #Differential # ... General #Ddxof
Diagnostic Schema for Hyperferritinemia

Pearl: Diseases associated with extreme elevations: 
1. HLH 
2. Still's disease 
3. Systemic
Diagnostic Schema ... Hyperferritinemia #Algorithm ... #Differential # ... Diagnosis #Hematology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... - Ichemic hepatitis ... Drug-Induced liver injury ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
Transaminitis - Differential ... Diagnosis • ... • Iatrogenic: DILI ... See Updated Schema ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... • Iatrogenic: DILI ... #diagnosis #algorithm ... #hepatology
Erythroderma - Diagnostic Algorithm. Pathophysiology: 1) Extensive cutaneous capillary dilation, results in widespread exfoliation of the
Erythroderma - Diagnostic ... Algorithm. ... #Dermatology #Rash ... #Differential # ... Ddxof