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hepatology lfts transaminitis causes hepatitis management obstetrics pathophysiology abnormal aflp albumin arterial ascites chemistry drug druginduced elevated embolism fatty function
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Diagnosis Framework ... Hepatopathy • Acute ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Injury (DILI) ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Algorithm DILI ... dechallenge • Acute ... #Injury #Diagnosis ... #Algorithm #hepatology
Evaluation abnormal liver tests in pregnancy - Cholestatic Pattern - Hepatocellular Pattern #LFTs #transaminits #pregnancy #obgyn #obstetrics #hepatology #diagnosis
Evaluation abnormal liver ... #obgyn #obstetrics ... #hepatology #diagnosis ... #differential # ... algorithm
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential ... Diagnosis Algorithm ... melanoma, myeloma • Pregnancy ... diagnosis #algorithm
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... injury - Viral ... #Causes #Differential ... #Hepatology #Diagnosis
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Injury #hepatology ... transaminitis #differential ... #diagnosis
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... infiltration) Differential ... #Pregnancy #hepatology ... #obstetrics #obgyn
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Toxic: Medication, Pregnancy ... #Injury #Differential ... #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
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