14 results
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... disease, Hepatic ischaemia ... e.g. ascites), Chronic ... #Diagnosis #Algorithm ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Cirrhosis • Chronic ... (>1000): • DILI ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Chest Pain - Differential Diagnosis Algorithm
Cardiovascular Causes:
 - Outflow Obstruction
     • Aortic
Chest Pain - Differential ... Diagnosis Algorithm ... Aortic Stenosis - Ischemic ... • Muscular Injury ... #Diagnosis #Algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : > 3 • Chronic ... #diagnosis #algorithm ... #hepatology
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Acute Kidney Injury ... (AKI) - Differential ... Other • ATN: Ischemia ... Diagnosis #nephrology ... #causes #algorithm
Renal Tubular Acidosis - Differential Diagnosis Algorithm
Decreased Serum K, Urine pH < 5.5 - Proximal RTA
Decreased
Diagnosis Algorithm ... Tubulointerstitial injury ... tract obstruction, Chronic ... #Diagnosis #Algorithm ... #nephrology
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
High-risk Features ... sulfa-drug - Skin pain ... #Dermatology #Rash ... #Differential # ... Ddxof
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Hyperkalemia - Differential ... Diagnosis Framework ... • Trauma/Crush injury ... burns, trauma - Ischemic ... #nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
Algorithm - Approach ... red blood cells/high-power ... , extremities (ischemia ... lymphadenopathy, pleuritic pain ... #Algorithm #differential