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differential causes liver acute lfts transaminitis hematology management pancytopenia abnormal aclf ah aki chronic cirrhosis criteria dili druginduced elevated failure
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... AST:ALT > 2.5 - Alcoholic ... Patterns #Liver #Injury ... #hepatology #LFTs ... #differential #diagnosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • Autoimmune ... • Drugs • AIH ... hepatitis • Drugs ... Others #LFTs #Hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Severe Acute Liver Injury ... - Ichemic hepatitis ... - Autoimmune ... #Differential #Hepatology ... #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential Diagnosis ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... #hepatology #algorithm
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
- Differential Diagnosis ... Algorithm Malignant ... Inflammatory • Alcoholic ... Hepatitis • Autoimmune ... #Hepatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis ... of Autoimmune Hepatitis ... factors - Possible ischemic ... #Hepatitis #Diagnosis ... #Hepatology #AIH
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
- Differential Diagnosis ... Algorithm for Transaminitis ... Drugs, Viral, Ischemia ... - NAFLD, Alcohol ... #diagnosis #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH) • Onset of jaundice within prior 8 weeks • Ongoing
of Alcoholic Hepatitis ... factors • Possible ischemic ... #diagnosis #Alcoholic ... #Hepatitis #AH ... #hepatology #criteria
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... steatosis • Autoimmune ... #Diagnosis #Algorithm ... #hepatology
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