10 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... Infection (EBV/CMV), Alcoholic ... AST:ALT > 2.5 - Alcoholic ... Patterns #Liver #Injury ... #hepatology #LFTs
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... - Ichemic hepatitis ... Drug-Induced liver injury ... - Autoimmune ... #Differential #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Drugs/Toxins • Ischemia ... • Autoimmune ... • NAFLD • Alcohol ... hepatitis • Drugs ... Others #LFTs #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... HSV • Toxic: Alcohol ... Other: NAFLD, Autoimmune ... Causes #Acute #algorithm ... #hepatology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Differential Diagnosis Algorithm ... Inflammatory • Alcoholic ... HepatitisAutoimmune ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Other: NAFLD, Autoimmune ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... steatosis • Autoimmune ... #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis of Autoimmune ... Hepatitis - Onset ... factors - Possible ischemic ... SMA >1:80 #Autoimmune ... #Hepatology #AIH
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Differential Diagnosis Algorithm ... Celiac disease • Autoimmune ... : Autoimmune hepatitis ... ALT Ratios: • Alcoholic ... #hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... - Acute kidney injury ... #Hepatitis #Management ... #Algorithm #hepatology