28 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver Injury ... 20x normal - Acute ... normal - Infection (EBV ... #hepatology #LFTs ... #differential #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Liver Injury - Differential ... Diagnosis Hepatocellular ... : Alcohol, Medication ... #Differential #Diagnosis ... #algorithm #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... severe liver injury ... > 3 mg/dL) or acute ... #HepBV #HBV #Treatment ... Indications #management #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
B - Diagnosis and ... Management Algorithm ... #HBV #Algorithm ... #Diagnosis #Management ... #Treatment #Hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury ... - Ichemic hepatitis ... Drug-Induced liver injury ... #Differential #Hepatology ... #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... #hepatology #algorithm ... Transaminitis #LFTs #hepatitis
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... #diagnosis #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Algorithm Severe ... Drugs/Toxins • Ischemia ... hepatitis • Drugs ... Others #LFTs #Hepatology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... injury with serum ... diseases including HBV ... #Algorithm #hepatology