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diagnosis management differential hematology injury liver lfts myelodysplastic acute anemia dili druginduced hepatocellular liverenzymes myelodysplasia syndrome syndromes transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • NAFLD • Alcohol ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Alcoholic Hepatitis - Management Algorithm 1. Severity assessed not only by MDF (>32) but also by MELD
Alcoholic Hepatitis ... - Management Algorithm ... assessed not only by MDF ... #Algorithm #treatment ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... HSV • Toxic: Alcohol ... - Sophia Hayes MD ... #Acute #algorithm ... #hepatology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... only curative treatment ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
treatments Search ... for alternative causes ... HEV, EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... Anemia: - Hepatitis ... anemia Treatment ... #Anemia #oncology ... #hematology #diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Lauren Banaszak, MD ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... exclude other causes ... #Hepatitis #Management ... #Algorithm #hepatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... arsenic compounds, alcohol ... factor (GCSF) treatments ... Syndromes #diagnosis #hematology ... #oncology
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