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diagnosis differential injury liver lfts hematology rheumatology transaminitis acute ascites classification diffuse dili druginduced eosinophilia fatigue hearingloss hepatocellular lad liverenzymes
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
normal - Infection (EBV ... /CMV), Alcoholic ... 5-10x normal - Chronic ... AST:ALT > 2.5 - Alcoholic ... Liver #Injury #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... , HBV, HCV, HEV, ... EBV, CMV), Alcohol-related ... disease, Hepatic ischaemia ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... : Alcohol, Medication ... Medication, Pregnancy, Alcoholic ... #Acute #algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Drugs/Toxins • Ischemia ... • NAFLD • Alcohol ... hepatitis • Drugs ... Others #LFTs #Hepatology ... #Causes
Causes of Peripheral Weakness with Sensory Changes - Differential Diagnosis Algorithm Radiculopathy: • Disc • Spondylosis •
Causes of Peripheral ... • Tumor • Ischemia ... Nutrition • Alcohol ... Multiplex: • Vasculitis ... Spondylysis • Chronic
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Differential Diagnosis Algorithm ... Tuberculosis • Hepatitis ... Age > 50 • Chronic ... #Causes #Hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... , HBV, HCV, HEV, ... ALT Ratios: • Alcoholic ... #hepatology
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... Epstein-Barr Virus • Hepatitis ... • HIV Autoimmune ... Alcohol) • Drug ... #causes
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Causes of Eosinophilia ... - Eosinophilic Hepatitis ... Asthma Tugs (vasculitis ... Hypereosinophilic Syndrome - Chronic ... #hematology
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