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diagnosis liver differential transaminitis alcoholic chemistry druginduced function hepatocellular interpretation management patterns rvalue tests
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... , HBV, HCV, HEV, ... disease, Hepatic ischaemia ... #Diagnosis #Algorithm ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Function Tests (LFTs ... (>1000): • DILI ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... Differential #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... > 50x normal - Ischemic ... normal - Infection (EBV ... Patterns #Liver #Injury ... #hepatology #LFTs
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... • Iatrogenic: DILI ... Chronic viral hepatitis ... #diagnosis #algorithm ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... serologies, HCV ... #differential #Hepatology ... transaminitis #LFTs
Alcoholic Hepatitis - Management Algorithm Assess Eligibility for Treatment: - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... - Acute kidney injury ... HCV, DILI, HCC, ... #hepatology
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