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causes hematology liver transaminitis workup acute classification emesis pancytopenia pediatrics peds vomiting dili elevated gastroenterology lactate macrocytic management mcv nausea
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
) - Differential ... 1000): • DILI (Drug-induced ... liver injury) ... • Ischemic Hepatopathy ... Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver Injury ... Patterns #Liver #Injury ... #hepatology #LFTs ... transaminitis #differential ... #diagnosis
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
- Ichemic hepatitis ... obstruction - Drug-Induced ... liver injury ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... valproate, azoles), Drugs ... • Vascular: Ischemic ... Diagnosis #hepatology ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Diagnosis Algorithm ... /Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... Diagnosis #Algorithm
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... disorder - TSH, LFTs ... Underproduction #Algorithm ... #hematology #diagnosis ... #differential #
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... disease, Hepatic ischaemia ... #Diagnosis #Algorithm ... #hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework LDH is a cytoplasmic enzyme present in tissues throughout
Dehydrogenase (LDH) - Differential ... Diagnosis Framework ... • Ischemic hepatitis ... inherited, acquired, drug ... #diagnosis #Laboratory
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... • Drug Induced ... #Diagnosis #Algorithm ... #Causes #Hepatology
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