13 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... disorder (e.g. ascites ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - Differential ... Cirrhosis • Chronic ... 1000): • DILI (Drug-induced ... • Ischemic Hepatopathy ... #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... presentation • Chronic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Differential Diagnosis ... onset (acute vs. chronic ... history (cardiac, liver ... renal disease), drug ... #Algorithm #Ddxof
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Volume (MCV) - Differential ... Diagnosis Algorithm ... Renal Disease, Liver ... Deficiency • Drugs ... #Causes #Hematology
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Cholangitis • Abscess ... Hepatitis • Drug ... #Causes #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... Diagnosis Algorithm ... /Toxins • Ischemia ... Others #LFTs #Hepatology
Causes of Altered Level of Consciousness GCS < 7 - Differential Diagnosis Algorithm

Brain Involvement - Hemispheric
Diagnosis Algorithm ... Traumatic • Ischemia ... • Neoplastic Abscess ... - Excesses • Liver ... Coma Systemic - Drugs
Causes of Seizures - Differential Diagnosis Algorithm
Unprovoked - Epilepsy:
 • Focal: Simple, Complex
 • Generalized: Absence,
of Seizures - Differential ... Diagnosis Algorithm ... , Recreational drugs ... Encephalitis, Brain Abscess ... Hypoxia, Uremia, Liver
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... valproate, azoles), Drugs ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis