13 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... > 20x normal - Acute ... 5-10x normal - Chronic ... #Patterns #Liver ... #Injury #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... EmoryGastroHep #ACLF #Acute ... #Chronic #Liver ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Chronic Diarrhea - Differential Diagnosis Algorithm
Steatorrhea
 - Maldigestive
    • Pancreatic Insufficiency
 - Primary
Differential Diagnosis Algorithm ... Overgrowth • Liver ... • Mesenteric Ischemia ... CoIits • Ischemic ... Screen with CBC, albumin
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Elevated Liver Function ... Cirrhosis • Chronic ... Hepatopathy • Acute ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Approach to Diarrhea - Differential Diagnosis and Workup Algorithm

Acute Diarrhea (MINT):
 • Medications
 • Infections: Inflammatory
Diagnosis and Workup Algorithm ... Acute Diarrhea ... radiation, ingestions ischemia ... ) Chronic Diarrhea ... #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... dechallenge • Acute ... or chronic atypical ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
presentation • Chronic ... or symptoms of liver ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Differential Diagnosis and Evaluation of Hyponatremia:
1) Identification of onset (acute vs. chronic)
2) Presence of symptoms (HA,
Identification of onset (acute ... vs. chronic) 2) ... history (cardiac, liver ... #Differential #Algorithm ... #Ddxof
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Mixed - Check Acute ... Production: • Albumin ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Hypoalbuminemia - Decreased albumin ... —100-fold with acute ... hepatocytes; in chronic ... suppression leads to chronic ... LiverFailure #Hepatic #Hepatology