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diagnosis differential lfts transaminitis causes albumin gradient abnormal aclf acute chronic dili druginduced elevated failure function gastroenterology hepatocellular hypertension liverenzymes
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
) SAAG ≥ 1.1: ... ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... #gradient #hepatology ... differential #diagnosis #algorithm
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Injury Transaminase ... CMV), Alcoholic cirrhosis ... #Patterns #Liver ... #Injury #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
Gradient (SAAG) ... - Alcoholic hepatitis ... - Massive liver ... associated with bowel ischemia ... Differential #Diagnosis #hepatology
Causes of Ascites Normal Peritoneum Portal hypertension (SAAG > 1.1 g/dL) 1. Hepatic congestionl
Liver disease ... - Cirrhosis ... - Alcoholic hepatitis ... - Acute fatty liver ... #differential #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... Chronic Viral Hepatitis ... • Acute Viral Hepatitis ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
those with CLD (± cirrhosis ... (AAH) Drug-Induced ... Liver Injury (DILI ... ) Viral Hepatitis ... #Hepatology #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Drugs • AIH ... • Alcoholic hepatitis ... Others #LFTs #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... disorder (e.g. ascites ... ), Chronic hepatitis ... #Algorithm #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
of portal HTN: ascites ... (SAAG>I.I), esophageal ... portal HTN: • Ascites ... /acute hepatitis ... Diagnosis #causes #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver ... • Vascular: Ischemic ... #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
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