8 results
diagnosis differential injury transaminitis causes function tests abnormal acute druginduced elevated gastroenterology hepatitis idiosyncratic induced interpretation laboratory liverenzymes liverfunctiontests management
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
100-500): • NAFLD ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Liver Injury (DILI ... Chronic - ongoing ↑ LFTs ... Calculate R-Value • Hepatocellular ... gastroenterology #algorithm ... gastroenterology #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Hepatocellular Liver ... valproate, azoles), Drugs ... • Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #LFTs #hepatitis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... alternative causes • Hepatocellular ... disease, Hepatic ischaemia ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Transaminitis Hepatocellular ... , Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... /Toxins • Ischemia ... ALT < 5x ULN • NAFLD ... • Others #LFTs ... #Hepatology #LiverEnzymes
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Differential Diagnosis Hepatocellular ... , Recreational Drugs ... Antitrypsin • Other: NAFLD ... Causes #Acute #algorithm ... #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... intrahepatic cholestasis, hepatocellular ... impaired uptake (drugs ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
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