11 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... 100-500): • NAFLD ... Cirrhosis • Chronic ... injury) • Ischemic ... Differential #Diagnosis #hepatology
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Infection (EBV/CMV ... 5-10x normal - Chronic ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... antitrypsin • Other: NAFLD ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Corpuscular Volume (MCV ... Differential Diagnosis Algorithm ... Renal Disease, Liver ... #MCV #Classification ... #Causes #Hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... disease, Hepatic ischaemia ... e.g. ascites), Chronic ... hepatitis fibrosis ... #hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Drugs, Viral, Ischemia ... Wilson's, HH, NAFLD ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
• Infectious: Hepatitis ... E, B, D, EBV, CMV ... Antitrypsin • Other: NAFLD ... Causes #Acute #algorithm ... #hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
Chronic Hepatitis ... and Management Algorithm ... anti-Hbe, HIV, HCV ... Chronic Hepatitis ... Management #Treatment #Hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... > 2 • NASH, Chronic ... injury: > 3 • Chronic ... #differential #Hepatology ... transaminitis #LFTs