18 results
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... 100-500): • NAFLD ... injury) • Ischemic ... Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... Injuryliver ... Injury Differential ... #Injury #Differential ... #LFTs #hepatitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
Patterns of Liver ... Injury Transaminase ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
liver disease algorithm ... or liver disease ... liver disease; ... #NAFLD #algorithm ... Referral #Management #Hepatology
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #diagnosis #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Injury - Differential ... Antitrypsin • Other: NAFLD ... #Injury #Differential ... Causes #Acute #algorithm ... #hepatology
NAFLD Diagnosis Algorithm
Two-step diagnostic strategy for NAFLD
1st step: 
  - Clinical biomarkers, scoring systems- FIB4,
Algorithm Two-step ... inspection of liver ... #NonAlcoholic #Fatty ... #Liver #Disease ... #Algorithm #hepatology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic ... hepatitis - Wilson disease ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Chronic - ongoing ↑ LFTs ... disease 6-9 mo ... #differential # ... gastroenterology #algorithm ... gastroenterology #hepatology