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diagnosis liver injury emesis hepatitis lfts neurology pediatrics vomiting abdominal aclf aflp aki alcoholic bradycardia chronic cirrhosis distention druginduced encephalopathy
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Idiosyncratic Drug-induced ... Idiosyncratic #differential ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... for alternative causes ... disease, Hepatic ischaemia ... dechallenge • Acute ... #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Hepatopathy • Acute ... (>1000): • DILI ... (Drug-induced liver ... injury) • Ischemic ... #Diagnosis #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe ... - Ichemic hepatitis ... obstruction - Drug-Induced ... #Causes #Differential ... #Hepatology #Diagnosis
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Hepatitis (AAH) Drug-Induced ... Liver Injury (DILI ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Causes of Acute Kidney Injury (AKI) - Differential Diagnosis Algorithm Acute Kidney Injury (AKI) - Acute increase
Causes of Acute ... Injury (AKI) - Differential ... Diagnosis Algorithm ... ) • Ischemia ( ... #Diagnosis #Algorithm
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... Diagnosis Algorithm ... /Toxins • Ischemia ... Others #LFTs #Hepatology ... #Causes
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Causes of Extravascular ... Diagnosis Algorithm ... anemia • Acute ... #Diagnosis #Algorithm ... #Causes #Hematology
Bradycardia Diagnostic and Management Algorithm CONSIDER ETIOLOGY (not inclusive): - STRUCTURAL: sick sinus, AV block, ischemia,
Diagnostic and Management ... Algorithm CONSIDER ... LIFE THREATENING CAUSES ... TREATMENT - Drugs ... #Differential
Causes of Pediatric Seizures - Differential Diagnosis Algorithm Infantile: • Benign Focal Epilepsy of Infancy • West
Causes of Pediatric ... Seizures - Differential ... Diagnosis Algorithm ... • Transient Ischemic ... #Causes #Peds #
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