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diagnosis differential liver pathophysiology aflp antiphospholipid arterial embolism essential et fatty hepatitis hus hypercoagulable injury lfts liverenzymes microangiopathy obstetrics portalvein
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... Intravenous Drug Use • Pregnancy ... Nephrotic Syndrome, Ischemic ... considered in all ... pathophysiology #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... • Wilson's • Pregnancy ... Others #LFTs #Hepatology ... #Causes
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
PVT) Treatment Algorithm ... If concern for ischemic ... - Cirrhosis: case-by-cased ... PVT #Treatment #management ... #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... = nonspecific (nausea ... #Fatty #Liver #Pregnancy ... #hepatology #obstetrics ... #obgyn #diagnosis
Thrombotic Microangiopathy - TMAs 1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
Thrombotic Microangiopathy ... TMAs cause MAHA ... (catastrophic APS ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Differential Diagnosis Algorithm ... Vascular Causes ... : Shock liver, Thrombosis ... melanoma, myeloma • Pregnancy ... #hepatology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome (APLS ... or small-vessel thrombosis ... • Unexplained pregnancy ... maternal chromosomal causes ... #diagnosis #hematology
Essential Thrombocythemia (ET) ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
first trimester pregnancy ... • Treatment algorithms ... Thrombocythemia #ET #hematology ... #diagnosis #management ... #hematology
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