10 results
Fever of Unknown Origin (FUO) - Further Workup

 • CNS symptoms? Get an LP and imaging
CNS symptoms ... Returning Traveler’ algorithm ... thin smear • Signs ... node biopsy • Clinical ... values supporting hematologic
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... Physical Exam/Signs ... microglobulin Treatment ... #oncology #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... - ACS, AKI, ... acute limb ischemia ... WBC >100k, + lab signs ... diagnosis #management #hematology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... ): - Hematologic ... ) - Symptoms: CNS ... ± tocilizumab; call
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... (Clinical Dx). ... retinal tears, Ischemia ... Arthritis, AS Treatment ... diagnosis #management #signs
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Diagnosis: HLH signs ... following: • Fever ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis: • Purpura, ischemic ... Vasculitis: • Fevers ... purpura: Strong sign ... CRP GCA (Giant Cell ... chorioretinitis, CNS
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
HLH is a critical ... Clinical Presentation ... • Common Signs ... Fever b. ... Diagnosis #Management #Hematology
Mitral valve regurgitation is the heart’s version of a plot twist — just when you think
degenerative disease, ischemic ... Clinically, it’s ... trying to make it all ... work. ... detective story, and treatment
Cryptococcal meningitis on T2 MRI
30 M from sub-Saharan Africa presents w/ progressive Headache x1 mo, +neck
low glucose) CNS ... organism (soap bubble sign ... Standard treatment ... amphotericin: Severe AKI ... T2 #MRI #Brain #clinical