13 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Diagnosis Algorithm ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... e.g. ascites), Chronic ... #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
dose dependent injury ... presentation • Chronic ... Idiosyncratic #differential ... gastroenterology #algorithm ... gastroenterology #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Cirrhosis • Chronic ... (>1000): • DILI ... Drug-induced liver injury ... ) • Ischemic Hepatopathy ... #Diagnosis #hepatology
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Chronic: ASCVD, ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments ... #Schema #Differential ... #Diagnosis #algorithm
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... vein: Budd-chiari syndrome ... : > 3 • Chronic ... #hepatology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... for workup, including ... Rebound effect from treatment ... Kawasaki, Nephrotic syndrome ... • Infections: Chronic
Acute Kidney Injury (AKI) in Patients with Cancer 

Cancer Related 
• Hypercalcemia 
• Intravenous contrast 
•
Acute Kidney Injury ... change disease • Hematologic ... malignancies Treatment ... #AKI #Cancer #Oncology ... #Differential #
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
> 2 • NASH, Chronic ... : > 3 • Chronic ... • Gilbert's syndrome ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... microglobulin Treatment ... • Richter’s Syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
to local skin injury ... Behcet disease) Differential ... retinal tears, Ischemia ... Arthritis, AS Treatment ... Recurrent and chronic