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causes hepatology transaminitis abnormal aptt coagulation prolonged acidosis activation algorithm arterial chemistry classification disorders elevation embolism function hepatitis hepatocellular hodgkins
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... #Injury #hepatology ... #LFTs #transaminitis ... #differential # ... diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... #Differential # ... Diagnosis #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury - Differential ... : Liver Injury ... Injury Differential ... #Injury #Differential ... #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Coagulation factors: PT ... #chemistry #diagnosis ... #differential # ... #LFTs #RValue #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... selected cases: INR/PT ... gastric bypass), LFT ... (liver disease) ... #Workup #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... the spleen or liver ... #oncology #diagnosis ... #differential # ... hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Early liver disease ... Reduced liver synthesis ... Prolonged #Causes #diagnosis ... #differential # ... hematology #coagulation
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Diagnosis Framework ... Nephrotic Syndrome, Ischemic ... Liver, IBD • ... Vasculitis • Injury ... pathophysiology #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... Diagnosis The ... or renal injury ... Injury: • Reduced ... Acidosis #Elevation #Differential
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