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diagnosis management hematology neurology cardiology syndrome causes anemia classification hepatology aih algorithm endocarditis erythematosus gravis hepatitis hodgkins lupus lymphoma microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... Extravascular #Causes #differential
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... thrombocythemia), Autoimmune ... disease • vWF ... #hematology #differential
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Immunosuppression (e.g ... diseases • Clinical ... diseases (e.g., ... Malignancies (eg ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Cerebrovascular Disease ... Lumbar Puncture, EEG ... Treatment: ... CNS #neurology #rheumatology
Clinical Diagnosis of Autoimmune Hepatitis - Onset of jaundice within prior 8 weeks - Ongoing consumption
Clinical Diagnosis ... factors - Possible ischemic ... hepatitis (e.g. ... use assessment (e.g ... laboratory tests (e.g
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
hemolytic anemia (e.g ... Microspherocytes: Autoimmune ... cells: Sickle cell disease ... Smear #Analysis #hematology ... interpretation #clinical
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Approach to Anemia - Differential ... - Extrinsic: Autoimmune ... aciduria, Drugs (e.g ... Non-megaloblastic: Liver disease ... #Diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... RBC #Morphology #differential ... #diagnosis #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor The maturation factor is
Chronic kidney disease ... infiltration (e.g ... Marrow suppression (e.g ... Intrinsic RBC defects (e.g ... #anemia #differential
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... Alcohol-related liver disease ... , Hepatic ischaemia ... vascular disorder (e.g ... steatosis • Autoimmune
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