19 results
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... of Systemic Lupus ... Cerebrovascular Disease ... #SLE #CNS #neurology ... #rheumatology #
BEE Syndromes - Immune-mediated conditions affecting the brain, eye, and ear

Visual or auditory symptoms in conjunction
central nervous system ... (CNS) involvement ... Sjögren syndrome • Systemic ... lupus erythematosus ... BEE #Syndromes #neurology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Systemic lupus ... Association with disease ... autoantibodies #Systemic ... #diagnosis #rheumatology ... #table #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Non-autoimmune rheumatologic ... and CNS • Headache ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
highly inflammatory disease ... • Systemic lupus ... (CNS) dysfunction ... lupus erythematosus ... #Rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Scleromyxedema (CNS ... to cold IgG • Lupus ... Sneddon-Wilkinson disease ... Paraproteinemias #Hematology
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
from Myocardial Ischemia ... associated with rheumatologic ... presentation of systemic ... lupus erythematosus ... Presentation #comparison #Table
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
: • Purpura, ischemic ... Others: • Lupus ... Kidneys: glomerular ischemia ... lupus erythematosus ... differential #diagnosis #rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
mainly AQP4-lgG disease ... pain • Extra-CNS ... autoimmune disorders (Systemic ... lupus erythematosus ... Manifestations #diagnosis #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... basal ganglia, CNS ... meningitis), MCC CNS ... retinal tears, Ischemia ... signs #symptoms #rheumatology