18 results
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... dys- (abnormal) -plastic ... old, ~10,000 new cases ... transformation to acute ... #oncology
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Aplastic Anemia ... Illness Script Signs ... and symptoms: ... progress to MDS or acute ... Anemia #diagnosis #management
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
and petechiae Causes ... • Improve the symptoms ... #Anemia #oncology ... #hematology #diagnosis ... #management
ISCHEMIA Trial - Management Algorithm for patients with Stable Angina

Stress Test -> ? +moderate or severe
Management Algorithm ... with a stable symptom ... This is not for acute ... coronary syndrome ... #Algorithm #Cardiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... - ACS, AKI, acute ... limb ischemia, ... WBC >100k, + lab signs ... TLS #diagnosis #management
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA)

1) Is visual loss caused
Anterior ischemic ... Definition: acute ... ischemic disorder ... Doppler US : halo sign ... Ophthalmology #Diagnosis #Algorithm
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Diagnosis and Management ... are not caused ... : ACUTE, fever, ... Sarcoidosis #Diagnosis #Management ... #Signs #Symptoms
Features of a Sickle Cell Crisis 
Sickle-cell disease - an autosomal recessive blood disorder.
Characterized by red
capillaries leading to ischaemia ... . 2) Aplasia - ... Acute worsening ... Crisis #Features #Signs ... #Symptoms
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Pure red cell aplasia ... ’s lymphoma or acute ... diagnosis #workup #oncology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... APML #diagnosis #management ... #hematology #oncology