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sle erythematosus syndrome systemic druginduced hematology summary activation anesthesia arthritis behcet cerebritis checklist classification cns comparison crisis differential disease gout
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... of SLE versus DIL ... life-threatening • Treatment ... Erythematosus #Diagnosis ... #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
that will cause ischemia ... permeability Diagnosis ... CNS #neurology #rheumatology ... #cerebritis #diagnosis ... #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
: • Purpura, ischemic ... Kidneys: glomerular ischemia ... such as systemic lupus ... purpura: strong sign ... #rheumatology #
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... constitutional symptoms • Treatment ... #DIL #rheumatology ... #diagnosis #treatment ... #management
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Antinuclear (ANA ... severe disease Treatment ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SJIA], systemic lupus ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
AKI, acute limb ischemia ... WBC >100k, + lab signs ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
knees, shoulders Signs ... : CLINICAL DIAGNOSIS ... exam and imaging Treatment ... Certolizumab, Golimumab), IL ... #management #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) Differential Diagnosis ... retinal tears, Ischemia ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology
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