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diagnosis differential management treatment vasculitis workup 2ndline afib anticoagulation arterial arteritis bleed bone cerebritis chads2 chads2vasc classification cns coronavirus covid19
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... Erythematosus #SLE #CNS #neurology ... #rheumatology #
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Causes of Thrombocytosis ... malignancies • Anemia ... Eric Strong @DrEricStrong ... - Strong Medicine ... #hematology #secondary
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Framework for Anemia ... Eric Strong @DrEricStrong ... - Strong Medicine ... differential #diagnosis #causes ... #hematology
CHA2DS2VASc vs HAS-BLED scores for stroke risk and bleed risk on anticoagulation C Congestive Heart Failure 1 H Hypertension 1 A2 Age >75 2 D Diabetes Mellitus 1 S2 Stroke,
HAS-BLED scores for stroke ... Mellitus 1 S2 Stroke ... Bleeding history/anemia ... CHADS2VASc #HASBLED #Comparison ... AFib #Diagnosis #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... - Strong Medicine ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... • Mechanism: ischemic ... differential #diagnosis #causes ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... (CVID, WAS), (neurologic ... changes), high MCV anemia ... or if a primary hematologic ... #Workup #hematology
Extrapulmonary manifestations of COVID-19 • Neurologic: Headaches, Dizziness, Encephalopathy, Guillain-Barré, Ageusia, Myalgia, Anosmia, Stroke • Renal:
of COVID-19 • Neurologic ... Ageusia, Myalgia, Anosmia ... , Stroke • Renal ... Gastrointestinal: Diarrhea, Nausea ... shock, Myocardial ischemia
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... result in severe anemia ... immune hemolytic anemia ... tissue damage from ischemia ... Diagnosis #Workup #Hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
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