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diagnosis hematology differential management cardiology endocarditis pathophysiology vasculitis algorithm arterial bone cerebritis classification clinical cns complications crisis cryofibrinogenemia dyspnea embolism
Cures for Sickle Cell disease #Sicklecell #sicklecelldisease #sicklecellanemia, #sicklecells #sickle #hematology #anemia #clinical #pediatrics #FOAM #FOAMed
Cures for Sickle ... Cell disease ... #Sicklecell #sicklecelldisease ... #sickle #hematology ... #anemia #clinical
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... in Sickle Cell Disease ... • Mechanism: ischemic ... #Joint #Pain #SickleCell ... #hematology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... prevention (statin for CVA
Sickle Cell Disease - Pathophysiology of disease and complications Due to the deformed shape, HbS induces
Sickle Cell Disease ... Pathophysiology of disease ... organs leading to ischemia ... #SickleCell #Disease ... Complications #Hematology
Causes of Dyspnea - Differential Diagnosis Algorithm Cardiac: • Dysrhythmia • Ischemia • Cardiomyopathy • Valvular disease
Causes of Dyspnea ... Dysrhythmia • Ischemia ... Superior vena cava ... • Anxiety • Anemia ... Diagnosis #Algorithm #Causes
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
chronic kidney disease ... Eric Strong @DrEricStrong ... - Strong Medicine ... differential #diagnosis #causes ... #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... - Strong Medicine ... Extravascular #Causes ... differential #diagnosis #hematology ... #anemia
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Sickle-cell disease ... Sickle cell disease ... capillaries leading to ischaemia ... of the baseline anaemia ... deficiency #SickleCell
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... result in severe anemia ... immune hemolytic anemia ... tissue damage from ischemia ... Diagnosis #Workup #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
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