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diagnosis hematology differential management altered anticoagulation antiphospholipid arterial breakthrough cerebritis cns cryofibrinogenemia dvt embolism erythematosus hypercoagulable leukostasis lupus lysis neurology
Causes of Approach to Altered Level of Consciousness - Workup Clinical Exam - Focal • Trauma •
Causes of Approach ... • Trauma • Stroke ... Hemorrhage • Ischemia ... Encephalitis #Altered #ALOC ... #workup #algorithm
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... autoantibodies that will cause ... ischemia and/or ... cyclophosphamide • Ischemic ... prevention (statin for CVA
Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot
Hypercoagulability ot Ca ... Behcet's disease - APLS ... - May-Thurner syndrome ... anticoagulation #hematology ... #differential #algorithm
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework VENOUS THROMBOSIS • Acquired Risk Factors: - >48 hours
Hyperviscosity, TTP, APLS ... • Nephrotic Syndrome ... , Ischemic Liver ... coagulation and other causes ... pathophysiology #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... visual changes, stroke ... AKI, acute limb ischemia ... diagnosis #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Related conditions: Stroke ... limb and bowel ischemia ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #hematology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... (APLS) Testing ... Hypercoagulable Workup ... maternal chromosomal causes ... #hematology
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