10 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... • NAFLD • Cirrhosis ... liver injury) • Ischemic ... Differential #Diagnosis #hepatology ... #transaminitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
for Transaminitis ... Drugs, Viral, Ischemia ... Congenital, Others, Cirrhosis ... Burak @kwburak #LFTs ... #hepatology #LiverFunctionTests
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... Drugs/Toxins • Ischemia ... Infiltrative • Cirrhosis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... Differential #Diagnosis #hepatology ... #algorithm #Transaminitis ... #LFTs #hepatitis
Giant Cell Arteritis (GCA) - Vasculitis Management Algorithm - ACR/VF 2021 Guidelines
 • Visual Symptoms/Loss or
) - Vasculitis Management ... Algorithm - ACR ... Critical Cranial Ischemia ... Critical Cranial Ischemia ... #rheumatology
Portal Vein Thrombosis (PVT) Treatment Algorithm
 - If concern for ischemic: anti-coag+multidisciplinary care
 - W/o cirrhosis+recent
PVT) Treatment Algorithm ... If concern for ischemic ... anti-thrombotic tx - Cirrhosis ... PVT #Treatment #management ... #Algorithm #hepatology
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... or symptoms of ... gastroenterology #algorithm ... gastroenterology #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... AKI, acute limb ischemia ... TLS #diagnosis #management ... #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
Algorithm regarding ... suspected HH based on symptoms ... Patients with cirrhosis ... #diagnosis #management ... #hepatology #gastroenterology