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diagnosis management differential algorithm rheumatology gastroenterology lfts causes liver oncology transaminitis ascites gradient saag vasculitis biliary bowel classification hemophagocytic hepatopulmonary
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
> 50x normal - Ischemic ... CMV), Alcoholic cirrhosis ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology
Indications for Albumin for Management of Cirrhosis • Large volume paracentesis (>5 liter) - 8g per
Indications for Albumin ... Management of Cirrhosis ... • Hepatorenal syndrome ... terlipressin #Albumin ... #treatment #hepatology
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
serum ascites albumin ... protein ≤ 2.5 g/dL: Cirrhosis ... Late Budd-Chiari syndrome ... SAAG #ascites #albumin ... #gradient #hepatology
Ascites Differential Diagnosis Table - Serum Ascites Albumin Gradient (SAAG) SAAG ≥ 1.1: • Cirrhosis • Portal
Serum Ascites Albumin ... SAAG ≥ 1.1: • Cirrhosis ... • Nephrotic syndrome ... #Table #Serum #Albumin ... Gradient #SAAG #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
>1.1 g/dl): - Cirrhosis ... ascites without cirrhosis ... - Nephrotic syndrome ... associated with bowel ischemia ... Differential #Diagnosis #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
• NAFLD • Cirrhosis ... liver injury) • Ischemic ... Differential #Diagnosis #hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... that will cause ischemia ... Puncture, EEG Treatment ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology
Hepatorenal Syndrome - Diagnosis and Management Summary Who gets HRS? • Decompensated cirrhosis • Typically with existing
Hepatorenal Syndrome ... Decompensated cirrhosis ... infection Mainstay of treatment ... circulatory overload, CV ischemia ... #Hepatorenal #Syndrome
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... changes, stroke symptoms ... AKI, acute limb ischemia ... organ damage • Treatment ... diagnosis #management #hematology
Portal Vein Thrombosis (PVT) Treatment Algorithm - If concern for ischemic: anti-coag+multidisciplinary care - W/o cirrhosis+recent
Thrombosis (PVT) Treatment ... If concern for ischemic ... multidisciplinary care - W/o cirrhosis ... anti-thrombotic tx - Cirrhosis ... management #Algorithm #hepatology
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