13 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Tests (LFTs) - ... Differential Diagnosis ... injury) • Ischemic ... Function #Tests #LFTs ... #hepatology #transaminitis
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
: Liver Injury ... Drugs (MDMA), Alcohol ... • Vascular: Ischemic ... #Diagnosis #hepatology ... Transaminitis #LFTs
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... - Differential Diagnosis ... Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... #hepatology #LiverFunctionTests
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential Diagnosis ... Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
Clinical diagnosis ... factors • Possible ischemic ... ) or metabolic liver ... #diagnosis #Alcoholic ... Hepatitis #AH #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... HEV, EBV, CMV), Alcohol-related ... Hepatic ischaemia ... #Injury #Diagnosis ... #Algorithm #hepatology
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... factors - Possible ischemic ... ) or metabolic liver ... Possible drug-induced liver ... #Hepatology #AIH
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... for HIV, HCV - Alcohol ... (CVID, WAS), (neurologic ... gastric bypass), LFT ... (liver disease)
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis

The most common causes of hyperlactatemia are usually:
, - regional ischemia ... or renal injury ... - regional ischemia ... - Mesenteric ischemia ... Hypoglycemia - Alcohol