56 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... #LFTs #transaminitis ... #differential #diagnosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... - Differential Diagnosis ... liver injury) • Ischemic ... Function #Tests #LFTs ... #hepatology #transaminitis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... Drugs/Toxins • Ischemia ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... symptoms of liver disease ... #Management #gastroenterology ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Vascular: Ischemic ... Hemochromatosis, Wilson's disease ... HELLP, Celiac disease ... #hepatology #algorithm ... Transaminitis #LFTs
"The majority of cases of acute mesenteric ischemia are the result of acute arterial occlusion resulting
acute mesenteric ischemia ... valvular heart disease ... SuperiorMesentericArtery #clinical #Diagnosis ... InferiorMesentericArtery #Gastroenterology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
- Differential Diagnosis ... cyst, Caroli's disease ... Parasitic infection, Ischaemic ... #differential #diagnosis ... #hepatology #gastroenterology
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Liver Injury - Ichemic ... hepatitis - Wilson disease ... #Differential #Hepatology ... #Diagnosis
Bradycardia Diagnostic and Management Algorithm

CONSIDER ETIOLOGY (not inclusive): 
 - STRUCTURAL: sick sinus, AV block, ischemia,
Bradycardia Diagnostic ... and Management ... sinus, AV block, ischemia ... lyme + tick bome diseases ... euglycemia - Ischemia
Chronic Diarrhea Differential Diagnosis
 • Inflammatory, Infectious: Recurrent C. diff, Giardiasis
 • Inflammatory, Non-infectious: IBD, Ischemia,
Diarrhea Differential Diagnosis ... Non-infectious: IBD, Ischemia ... overgrowth, Celiac disease ... #Differential #Diagnosis ... #causes #gastroenterology