29 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... > 20x normal - Acute ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology
Approach to Diarrhea - Differential Diagnosis and Workup Algorithm

Acute Diarrhea (MINT):
 • Medications
 • Infections: Inflammatory
and Workup Algorithm ... Acute Diarrhea ... Necrosis • Toxic (e.g ... radiation, ingestions ischemia ... #Algorithm #gastroenterology
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Mesenteric Ischemia ... GPA, IgA, MPA) Acute ... inflammation (e.g ... hypovolemia), Meds/Treatments ... #Mesenteric #Ischemia
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Causes of Severe Acute ... Liver Injury - Ichemic ... hepatitis - Acute ... #Differential #Hepatology ... #Diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
that will cause ischemia ... permeability Diagnosis ... Lumbar Puncture, EEG ... Treatment: ... cyclophosphamide • Ischemic
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... → Refer to hematology ... for workup, including ... Rebound effect from treatment ... #Algorithm #hematology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
- Differential Diagnosis ... Hepatopathy • Acute ... liver injury) • Ischemic ... #Differential #Diagnosis ... #hepatology #transaminitis
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
- Differential Diagnosis ... Parasitic infection, Ischaemic ... #differential #diagnosis ... #hepatology #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
DILI) - Stepwise Diagnosis ... non-essential drug/HDS treatments ... disease, Hepatic ischaemia ... dechallenge • Acute ... #Algorithm #hepatology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... limb ischemia, ... unless worrisome EKG ... Syndrome #TLS #diagnosis ... #management #hematology