31 results
Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Hypereosinophilic Syndrome ... #HES #Hematology ... #eosinophilia # ... eosinophils #diagnosis ... #management #algorithm
Hypereosinophilia Syndrome (HES) - Diagnosis and Management
Definition: An absolute eosinophil count (AEC) greater than 1500 and
Hypereosinophilia Syndrome ... Diagnosis and Management ... Hypereosinophilia #Syndrome ... #diagnosis #hematology ... #differential #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... Cerebrovascular Disease ... that will cause ischemia ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
hepatitis • Ischemic ... distinguishes ischemic ... injury • Demand ischemia ... • Tumor lysis syndrome ... Polyarteritis nodosa • Eosinophilic
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
Sickle Cell Disease ... Pathophysiology of disease ... organs leading to ischemia ... #SickleCell #Disease ... Complications #Hematology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
cyst, Caroli's disease ... sludge), Mirizzi's syndrome ... Parasitic infection, Ischaemic ... differential #diagnosis #hepatology
Eosinophilic Gastroenteritis: Treatment Options Based on Severity of the Disease
Mild:
 • Trial of PPI
 • Trial
Eosinophilic Gastroenteritis ... Severity of the Disease ... Concern for HES: • Hematology ... scan #EoE #Eosinophilic ... Gastroenteritis #Treatment #management
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
polychondritis, GPA • Ischemic ... GI - Felty syndrome ... • Felty's syndrome ... Amyloidosis • Eosinophilic ... differential #diagnosis #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
in Sickle Cell Disease ... • Mechanism: ischemic ... Pain #SickleCell #Disease ... diagnosis #causes #hematology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
• Budd-Chiari syndrome ... Irritable bowel syndrome ... Chronic mesenteric ischemia ... • Mesenteric ischemia ... pseudoobstruction • Eosinophilic