33 results
Patterns of Liver Injury
Transaminase Levels:
  > 50x normal - Ischemic Hepatitis
  > 20x normal
> 50x normal - Ischemic ... AST:ALT = 1 - Ischemia ... Viral Hepatitis, Ischemic ... Liver #Injury #hepatology ... #LFTs #transaminitis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... liver injury) • Ischemic ... Function #Tests #LFTs ... Differential #Diagnosis #hepatology
 End Stage Liver Disease (Cirrhosis) - Complications 
 • Ascites
 • Esophageal Varices
 • Hepatic
(Cirrhosis) - Complications ... Hepatopulmonary Syndrome ... • Hepatorenal Syndrom ... #diagnosis #management ... #summary #hepatology
Management and Complications of Cirrhosis and Ascites

Ascites Workup Algorithm
Ascites Management
Refractory Ascites
Hyponatremia
Spontaneous Bacterial Peritonitis (SBP)
Hepatic Hydrothorax
AKI in
Management and Complications ... Algorithm Ascites Management ... Cirrhosis #Ascites #Complications ... #gastroenterology ... #hepatology
Causes of Biliary Dilatation - Differential Diagnosis
 • Physiological: ↑ Age, Cholecystectomy, Opioid dependence, Post-sphincterotomy
 •
sludge), Mirizzi's syndrome ... Parasitic infection, Ischaemic ... differential #diagnosis #hepatology ... #gastroenterology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Drugs/Toxins • Ischemia ... • Others #LFTs ... #Hepatology #LiverEnzymes
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI)

DILI Types:
 • Intrinsic - predictable, dose dependent
Diagnosis and Management ... Chronic - ongoing ↑ LFTs ... #gastroenterology ... #algorithm #gastroenterology ... #hepatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Demyelinating Syndrome ... that will cause ischemia ... cyclophosphamide • Ischemic ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Sickle Cell Disease - Pathophysiology of disease and complications 

Due to the deformed shape, HbS induces
of disease and complications ... organs leading to ischemia ... Pathophysiology #Complications ... #Hematology #Sequelae
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Drugs, Viral, Ischemia ... Burak @kwburak #LFTs ... Algorithm #diagnosis #hepatology