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acute lfts management transaminitis aclf anemia bilirubin chemistry cirrhosis classification conjugated direct drug druginduced erythrocytosis failure function hepatitis hyperbilirubinemia idiosyncratic
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Injury (DILI) ... presentation • Chronic ... #differential # ... #algorithm #gastroenterology ... #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Injury (DILI) - ... Algorithm DILI ... for alternative causes ... #Injury #Diagnosis ... #Algorithm #hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Diagnosis Framework ... Cirrhosis • Chronic ... (>1000): • DILI ... injury) • Ischemic ... #Diagnosis #hepatology
Liver Mass - Differential Diagnosis Algorithm Benign Cystic • Cyst • Polycystic Liver Disease • Caroli's
Liver Mass - Differential ... Diagnosis Algorithm ... #Mass #Hepatology ... Diagnosis #Algorithm ... #Causes
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Cirrhosis #Hepatology ... #gastroenterology ... #management #diagnosis
Liver Mass - Differential Diagnosis Algorithm Cystic: • Benign - Simple: Simple
Liver Mass - Differential ... Diagnosis Algorithm ... #Mass #Differential ... #Diagnosis #Algorithm ... #Causes #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... diagnosis #algorithm ... #hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... Diagnosis Algorithm ... #Diagnosis #Algorithm ... #Causes #Hematology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Diagnosis Algorithm ... MRCP, ERCP, liver ... #Diagnosis #Algorithm ... #gastroenterology ... #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Liver Injury - Differential ... #Injury #Differential ... #Diagnosis #Causes ... #Acute #algorithm ... #hepatology
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