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diagnosis differential causes injury anemia dili lfts management acute druginduced macrocytic mcv transaminitis abnormal aclf alkaline alp bilirubin bleeding bruising
Diagnosis and Management of Idiosyncratic Drug-induced Liver Injury (DILI) DILI Types: • Intrinsic - predictable, dose dependent
Drug-induced Liver ... EmoryGastroHep #DILI #Drug ... Diagnosis #Management #gastroenterology ... #algorithm #gastroenterology ... #hepatology
Drug-Induced Liver Injury - Pathophysiology Indirect Idiosyncratic Direct BWH Medicine Chiefs @BrighamChiefs #DILI #DrugInduced #Liver #Injury #Pathophysiology #hepatology
Drug-Induced Liver ... Pathophysiology Indirect Idiosyncratic ... #DrugInduced #Liver ... Pathophysiology #hepatology
Approach to Hypoproliferative Macrocytic Anemia • 812, Folate Deficiency • MDS+ • Hypothyroid • Liver Disease
Hypothyroid • Liver ... • Alcohol • Drugs ... differential #diagnosis #algorithm ... #hematology #workup
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic Liver ... disease, liver ... Hepatitis (AAH) Drug-Induced ... Failure #Cirrhosis #Hepatology ... #gastroenterology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Drug Induced Liver ... Stepwise Diagnosis Algorithm ... exposure to HDS, drugs ... Injury #Diagnosis #Algorithm ... #hepatology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Differential Diagnosis Algorithm ... MRCP, ERCP, liver ... Differential #Diagnosis #Algorithm ... #gastroenterology ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... Differential Diagnosis Algorithm ... • Viral • Drugs ... Others #LFTs #Hepatology ... Differential #Diagnosis #Algorithm
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Differential Diagnosis Algorithm ... Non-Malignant • Fatty Liver ... Hepatitis • Drug ... Differential #Diagnosis #Algorithm ... #Causes #Hepatology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Differential Diagnosis Algorithm ... Renal Disease, Liver ... Deficiency • Drugs ... Reticulocytosis • Liver ... #Causes #Hematology
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
Algorithmic Approach ... Orotic aciduria, Drugs ... Non-megaloblastic: Liver ... #Anemia #MCV #Algorithm ... Differential #Diagnosis #hematology
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