22 results
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
• Pain: Due to nerve ... Guillain-Barre Diagnosis ... roots and cauda ... #diagnosis #management ... #treatment #neurology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tumor • Motor Nerves ... Guillain-Barre syndrome ... #differential #diagnosis ... #neurology
Lower Extremity Dermatomes and Myotomes
Reflexes: 
 • Knee - L2, L3, L4
 • Ankle - S1
Conditions: • Cauda ... Equina Syndrome ... damage to peroneal nerve ... claudication and weakness ... #neurology #sensory
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
Diagnosis Framework ... • Acute stroke syndromes ... aminotransferases • Serology ... #Differential #Diagnosis ... #neurology
CN III Palsy - Oculomotor Nerve
 • Ptosis: Loss of innervation of the levator palpebrae superior.
Palsy - Oculomotor Nerve ... comparison to Horner's syndrome ... Extraocular Muscle Weakness ... #Cranial #neurology ... #diagnosis
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Cauda Equina Syndrome ... compression of nerve ... Differential Diagnosis ... lower extremity weakness ... #causes #neurology
Incomplete spinal cord syndromes (ISCS)
 • Central - Small Lesion - Suspended sensory deficit, classic cape
Incomplete spinal cord syndromes ... sign, variable weakness ... LMN types) • Cauda ... Incomplete #spinalcord #syndromes ... #diagnosis #neurology
NINDS Diagnostic Criteria for Guillain Barre Syndrome 
Features Required for Guillain-Barré Syndrome:
 • Progressive muscle weakness
Progressive muscle weakness ... Progression of weakness ... signs, Cranial nerve ... persistent asymmetry of weakness ... #neurology #neuropathy
Causes of Hemiplegia - Differential Diagnosis Algorithm
Cerebral Hemisphere (Contralateral motor cortex)
 • Aphasia
 • Apraxia
 •
- Differential Diagnosis ... Consciousness • Cranial Nerve ... Brown-Sequard Syndrome ... ipsilateral to weakness ... #Hemiplegia #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... roots and cauda ... Guillain #Barre #Syndrome ... #diagnosis #management ... #neurology