12 results
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , Acute hemolysis ... #Diagnosis #Algorithm ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Lymphoma - Comparison ... Alcohol-induced pain ... : Pain in involved ... #differential # ... hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... inclusions - If infection ... #Diagnosis #Algorithm ... #workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
DIC/TTP/HUS - Hemolytic ... - APLS • Acute ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
burning sensation or pain ... Diagnosis: Vasculitis ... disease • Non-Hodgkin ... Polyangiitis #GPA #dermatology ... #rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... nodosum • Immune hemolytic ... anemia • Pain ... number of sites of disease ... classification #hematology
Reticulocyte Production Index = (Retic %) x (Hct / 45) / Maturation Factor
The maturation factor is
Chronic kidney disease ... infiltration (e.g. cancer ... Index > 3: • Acute ... Production #Index #hematology ... #anemia #differential
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Diagnosis: • hemolytic ... younger pts) Differential ... chills, flank pain ... #hematology #diagnosis
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... - Gout • Jaundice ... , Vasculitis (e.g ... #differential # ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... cyclophosphamide) • Hodgkin ... #Rheumatology