12 results
Thrombocytosis - Differential Diagnosis
Platelet Count > 450
Reactive:
 • Anemia/blood loss (Fe deficiency)
 • Infection/Sepsis
 • Non-infectious
Differential Diagnosis ... Platelet Count ... Reactive: • Anemia ... Diagnosis #causes ... #Platelets #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Elevated Platelet ... → Refer to hematology ... for workup, including ... #Platelets #Differential ... #hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
Causes of Thrombocytosis ... effect following treatment ... following EtOH induced thrombocytopenia ... Iron deficiency anemia ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Diagnosis and Workup ... History: - Prior platelet ... #Platelet #Disorders ... #Workup #hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
RBC's secondary to platelet ... • Platelet defects ... NON-PALPABLE PURPURA: Platelet ... #Diagnosis #hematology ... #nonpalpable #dermatology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
abnormality is platelet ... widely varying platelet ... following: • Platelet ... #hematology #diagnosis ... #management #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential ... with or without platelet ... Schistocytes, thrombocytopenia ... #workup #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
for Thrombotic Thrombocytopenic ... intravascular hemolysis Platelet ... and decreased platelet ... WBC count and differential ... #Workup #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
to a low blood platelet ... neutrophils and platelets ... Neutropenia • Platelet ... blood cells or platelets ... #hematology #oncology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Findings in DIC: • Platelet ... - Platelet rich ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology