20 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
- Acute biliary ... - Autoimmune ... hepatitis - Wilson ... Hemochromatosis - Primary biliary ... #Differential #Hepatology
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... • Increased bilirubin ... hepatocyte damage (eg, hepatitis ... postoperative jaundice ... neoplasms #Jaundice
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis of Autoimmune ... Hepatitis - Onset ... - Serum total bilirubin ... SMA >1:80 #Autoimmune ... #Hepatology #AIH
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
Function Tests (LFTs ... (GGT) - Liver, biliary ... Conjugated/DBili) - Biliary ... Function #Tests #LFTs ... Interpretation #diagnosis #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Ischemia • Autoimmune ... • Alcoholic hepatitis ... Duct Stone • Biliary ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Autoimmune ... Hepatitis • Drug ... Induced Hepatitis ... Cholangitis • Primary Biliary ... Algorithm #Causes #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Inflammation - Hepatitis ... 15 percent) - Hepatitis ... Schistosomiasis - Autoimmune ... congenital - Primary biliary ... #Differential #Hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm
Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort
Signs: Jaundice, Xanthelasmata, Hepatomegaly
Associated history:
Primary Biliary ... discomfort Signs: Jaundice ... of associated autoimmune ... #PBC #Primary #Biliary ... Diagnosis #Algorithm #hepatology
Clinical diagnosis of Alcoholic Hepatitis (AH)
 • Onset of jaundice within prior 8 weeks
 • Ongoing
diagnosis of Alcoholic Hepatitis ... ) • Onset of jaundice ... before the onset of jaundice ... • Serum total bilirubin ... #AH #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Other: NAFLD, Autoimmune ... hepatitis, Acute ... biliary obstruction ... Extrahepatic • Biliary ... Acute #algorithm #hepatology