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diagnosis hepatology differential causes management algorithm syndrome gastroenterology ascites lfts rheumatology acute injury transaminitis abnormal classification clinical comparison elevated laboratory
Clinical Examination for Liver and Biliary Diseases 1) Hands: Clubbing, Dupuytren's contracture, Leuconychia, Bruising, Flapping tremor (hepatic
Examination for Liver ... and Biliary Diseases ... Xanthelasma and jaundiced ... #physicalexam #cirrhosis ... #liver #disease
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Etiologies of Cirrhosis ... Inflammation - Hepatitis ... 15 percent) - Hepatitis ... congenital - Primary biliary ... Nonalcoholic fatty liver
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 Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... /Liver failure ... hyperpigmentation • Jaundice ... or higher • Liver ... Diagnosis: • Viral hepatitis
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
/acute hepatitis ... • Infiltrative diseases ... sarcoidosis) • Liver ... pregnancy • Primary biliary ... Veno-occlusive disease
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
of Severe Acute Liver ... - Acute biliary ... - Drug-Induced liver ... - Wilson disease ... Hemochromatosis - Primary biliary
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
Diagnosis Chronic liver ... disease (cirrhosis ... or chronic hepatitis ... failure - 3-5% Cirrhosis ... Failure, Pancreatic, Biliary
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... Cirrhosis - Diagnosis ... discomfort Signs: Jaundice ... of autoimmune disease ... Liver biopsy findings
Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Non-Malignant • Fatty Liver ... Hemochromatosis • Wilson's Disease ... Infectious • Hepatitis ... Cholangitis • Primary Biliary ... Cirrhosis #Hepatomegaly
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... , Toxic Hepatitis ... CMV), Alcoholic cirrhosis ... , Portal Vein Thrombosis ... #Patterns #Liver
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Disease: Primary ... Biliary Cirrhosis
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