8 results
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... excretion of bilirubin conjugates ... Dysfunction - Biliary ... postoperative jaundice ... neoplasms #Jaundice
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... II) Hepatic - Conjugated ... on Ultrasound Biliary ... Gallstones • Biliary ... Cholangitis #Jaundice
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... hyperpigmentation • Jaundice ... No extrahepatic biliary ... malignancy #Primary #Biliary
Clonorchiasis - Clonorchis sinensis Life Cycle
1) Embryonated eggs passed in feces.
2) Eggs ingested by the snail
6) Adults in biliary ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
African Trypanosomiasis - Trypanosoma brucei gambiense & Trypanosoma brucei rhodesiense Life Cycle
1) Tsetse fly takes a
Trypomastigotes multiply by binary ... tryposmatigotes multiply by binary ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Trypanosomiasis - Trypanosoma cruzi Life Cycle
1) Triatomine bug takes a blood meal (passes metacyclic trypomastigotes in
Amastigotes multiply by binary ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc
Fasciola hepatica - Liver Fluke Life Cycle - Fascioliasis 
Ruminants are the typical definitive hosts.
1) Unembroynated
parenchyma to biliary ... flukes in hepatic biliary ... LifeCycle #diagnosis #pathophysiology ... infectiousdiseases #cdc