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diagnosis differential liver algorithm causes hematology hepatitis laboratory metabolism cirrhosis hyperbilirubinemia lfts aflp anemia biliary chemistry classification congenital gastroenterology hemolysis
Bilirubin Metabolism - Pathophysiology • Conjugated Bilirubin • Unconjugated Bilirubin By Dr. Khushboo Gala @LouLectures #Bilirubin #Metabolism #Pathophysiology
- Pathophysiology ... • Conjugated ... Bilirubin • Unconjugated ... #Metabolism #Pathophysiology ... #hepatology #Liver
Biochemistry and Metabolism of Bilirubin Hemolysis → Hemoglobin → Heme → Biliverdin → Unconjugated Bilirubin (a.k.a. "indirect
→ Biliverdin → Unconjugated ... Conjugation → Conjugated ... , and conjugated ... Biochemistry #Metabolism #pathophysiology ... #hepatology
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... conjugates (eg, ... postoperative jaundice ... neoplasms #Jaundice ... Classification #diagnosis #conjugated
Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... an increase in conjugated ... #hepatology #diagnosis
Jaundice - Pathophysiology and Causes - Amy Chung, MD, MSc @AmyChung #Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... @AmyChung #Jaundice ... #Pathophysiology ... #Differential #Unconjugated
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Pre-Hepatic - Unconjugated ... II) Hepatic - Conjugated ... Cholangitis #Jaundice ... Algorithm #Causes #Hepatology
Bilirubin metabolism and pathophysiology of jaundice #Bilirubin #metabolism #pathophysiology #jaundice #hepatology
Bilirubin metabolism ... and pathophysiology ... of jaundice # ... #pathophysiology ... #jaundice #hepatology
Inherited forms of Hyperbilirubinemia Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
pathways involved in bilirubin ... bilirubin into ... Decreased MRP2 - Conjugated ... Hyperbilirubinemia #pathophysiology ... #congenital #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Phosphatase and Bilirubin ... cytochromes) • Unconjugated ... MRP2 transports conjugated ... bilirubin into ... #Hepatology #Pathophysiology
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm 1. Definition: T.bili elevation + >20% conjugated 2. Obtain RUQ
Approach to Conjugated ... elevation + >20% conjugated ... MatthewHoMD #Conjugated ... Hyperbilirubinemia #direct #bilirubin ... gastroenterology #hepatology
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