132 results
Algorithm and Differential Diagnosis of Hyperbilirubinemia 
Direct = Conjugated
Indirect = Unconjugated

#Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Hyperbilirubinemia Direct = Conjugated ... Indirect = Unconjugated ... Jaundice #Hyperbilirubinemia ... Direct #Indirect #Conjugated ... #Unconjugated #
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic

#Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated

** GrepMed Recommended
Causes of Jaundice ... Extrahepatic #Diagnosis ... #Differential #Jaundice ... #Extrahepatic #Unconjugated ... #Conjugated
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Algorithm #Diagnosis ... Management #EM #IM #GI #Jaundice ... Direct #Indirect #Conjugated ... #Unconjugated #
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Unconjugated hyperbilirubinemia ... drug reactions) Conjugated ... Classification #diagnosis ... #conjugated #unconjugated ... #differential #causes
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Diagnosis Algorithm ... Pre-Hepatic - Unconjugated ... II) Hepatic - Conjugated ... #Algorithm #Causes
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... @AmyChung #Jaundice ... #Differential #Unconjugated ... #Causes #Diagnosis
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
Bilirubin - Unconjugated ... Indirect) - Conjugated ... LFTs #Laboratory #Diagnosis
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
, intermittent unconjugated ... UGT1A1 activity • Unconjugated ... and stress may cause ... an increase in conjugated ... and unconjugated
Inherited forms of Hyperbilirubinemia
Major pathways involved in bilirubin production, conjugation, and excretion. Notes: Both the UB
for transporting unconjugated ... absent UGT1A1 - Unconjugated ... Decreased MRP2 - Conjugated ... Decreased OATP1B - Conjugated ... hepatology #pediatrics #peds
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
Approach to Conjugated ... - Differential Diagnosis ... elevation + >20% conjugated ... non-ICU vs ICU causes ... MatthewHoMD #Conjugated