11 results
diagnosis algorithm aflp anemia hematology injury obstetrics pregnancy transaminitis biliary chemistry cholangitis cirrhosis comparison conjugated disease fatty hellp icp infections
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... 2-5x normal - Hemolysis ... #Injury #hepatology ... #LFTs #transaminitis ... #differential #
Classification of Jaundice Unconjugated hyperbilirubinemia (predominantly indirect bilirubin) • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of ... production (eg, hemolytic ... anemias, hemolytic ... hepatocyte damage (eg, hepatitis ... #unconjugated #differential
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... #classification ... #hematology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... Check Acute viral hepatitis ... #diagnosis #differential ... #Hepatology #transaminitis ... #LFTs #RValue #
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Volume (MCV) - Differential ... • Bleeding • Hemolysis ... #Anemia #MCV #Classification ... #Hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes ... Diagnosis #Algorithm #Causes
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Pruritus, Mild jaundice ... HELLP Syndrome (Hemolysis ... Disease #Pregnancy #hepatology ... #obstetrics #hepatitis ... #comparison #differential
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Algorithm Vascular Causes ... #injury #hepatitis ... #differential # ... diagnosis #algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... (DIC, ascites, jaundice ... infiltration) Differential ... Diagnosis: Viral Hepatitis ... #Pregnancy #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... hyperpigmentation • Jaundice ... bile ducts Differential ... Diagnosis: • Viral hepatitis ... diagnosis #workup #hepatology
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