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diagnosis hematology differential abnormal coagulation liver prolonged algorithm management pt abscess air biliary bilirubin bilirubinemia bleeding bruising calling children cholangitis
How to Evaluate an Abnormal APTT Step 1: Is the PT or APTT Artifactually Prolonged? Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... K Antagonists, Heparin ... to identify the cause ... prolonged #diagnosis #hematology
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Jaundice - Differential ... Algorithm Pre-Hepatic ... Cholangitis #Jaundice ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... unfractionated heparin ... Pre-analytical cause ... e.g. heparin ... #differential #hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... (e.g. heparin contamination ... thrombin inhibitors, heparin ... #differential #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Treat primary cause ... 100mg/dL) - Heparin ... INR < 2.3 - APTT ... Coagulation #diagnosis #causes ... treatment #management #hematology
Portal venous gas on hepatic ultrasound: A concerning finding in the critically ill patient that should
venous gas on hepatic ... of air in the hepatic ... variety of other causes ... venousgas #ultrasound #hepatology ... #liver #pocus #
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 Inherited Non-hemolytic Disorders of Hyperbilirubinemia == Disorders of Conjugation == Gilbert Syndrome: • 5-10% of the population
breastfeeding jaundice ... and stress may cause ... • Defect in hepatic ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
The Liver Consult Primer - Guide to calling a consult HPI: - Start with reason for consult
Important findings: jaundice ... different) PMHx: - Focus ... Calling #Referral #Hepatology ... #Gastroenterology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... hyperpigmentation • Jaundice ... malignancies, Hepatic ... diagnosis #workup #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
NORMAL PT/NORMAL PTT ... Acquired: • Heparin ... the PT and the PTT ... discern these causes ... Differential #Diagnosis #Hematology
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