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Jaundice Differential Diagnosis: A short guide

By Dr. Khudhur Mohammed @khudhur_moh

#jaundice #gastroenterology #algorithm #differential #diagnosis #hyperbilirubinemia #bilirubin
Jaundice Differential ... khudhur_moh #jaundice ... #gastroenterology ... differential #diagnosis #hyperbilirubinemia
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
common hereditary hyperbilirubinemia ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... hepatology #diagnosis #gastroenterology
Algorithm and Differential Diagnosis of Hyperbilirubinemia 
Direct = Conjugated
Indirect = Unconjugated

#Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Differential Diagnosis of Hyperbilirubinemia ... #Diagnosis #Jaundice ... #Hyperbilirubinemia
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Management #EM #IM #GI #Jaundice ... #Hyperbilirubinemia
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... - Unconjugated Hyperbilirubinemia ... Hepatic - Conjugated Hyperbilirubinemia ... Cholangitis #Jaundice
Approach to Neonatal Jaundice

Causes of pathologic hyperbilirubinemia can be classified as due to (1) increased bilirubin
Approach to Neonatal Jaundice ... of pathologic hyperbilirubinemia ... Pediatrics #Neonatal #Jaundice
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Unconjugated hyperbilirubinemia ... posthepatitis hyperbilirubinemia ... postoperative jaundice ... neoplasms #Jaundice
Jaundice: Yellow skin discoloration caused by hyperbilirubinemia.

Charlie Goldberg, M.D. - UCSD Catalog of Clinical Images

#Clinical #Photo
Jaundice: Yellow ... discoloration caused by hyperbilirubinemia ... Dermatology #Skin #Jaundiced
Approach to Conjugated Hyperbilirubinemia - Differential Diagnosis Algorithm

1. Definition: T.bili elevation + >20% conjugated
2. Obtain RUQ
to Conjugated Hyperbilirubinemia ... #Conjugated #Hyperbilirubinemia ... Diagnosis #Algorithm #gastroenterology
Isolated Hyperbilirubinemia - Differential Diagnosis Algorithm
Direct Hyperbilirubinemia: Dubin-Johnson Syndrome, Rotor Syndrome
Indirect Hyperbilirubinemia: 
 - Trauma, Hematoma,
Isolated Hyperbilirubinemia ... Algorithm Direct Hyperbilirubinemia ... Syndrome Indirect Hyperbilirubinemia ... Dyserythropoiesis #Hyperbilirubinemia