248 results
Algorithm and Differential Diagnosis of Hyperbilirubinemia 
Direct = Conjugated
Indirect = Unconjugated

#Diagnosis #Jaundice #Hyperbilirubinemia #Differential #Algorithm #Direct
Hyperbilirubinemia Direct = Conjugated ... Indirect = Unconjugated ... #Diagnosis #Jaundice ... Direct #Indirect #Conjugated ... #Unconjugated #
Jaundice Evaluation Algorithm #Diagnosis #Management #EM #IM #GI #Jaundice #Hyperbilirubinemia #Workup #Evaluation #Differential #Algorithm #Direct #Indirect
Jaundice Evaluation ... Algorithm #Diagnosis #Management ... #EM #IM #GI #Jaundice ... Direct #Indirect #Conjugated ... #Unconjugated #
Causes of Jaundice - Prehepatic, Intrahepatic, Extrahepatic

#Diagnosis #Differential #Jaundice #Prehepatic #Intrahepatic #Extrahepatic #Unconjugated #Conjugated

** GrepMed Recommended
Causes of Jaundice ... #Differential #Jaundice ... #Extrahepatic #Unconjugated ... #Conjugated
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Classification of Jaundice ... Unconjugated hyperbilirubinemia ... postoperative jaundice ... neoplasms #Jaundice ... #unconjugated #
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
Jaundice - Differential ... Pre-Hepatic - Unconjugated ... • Gilbert's Syndrome ... Crigler-Najjar Syndromes ... Cholangitis #Jaundice
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
hyperbilirubinemia syndrome ... breastfeeding jaundice ... and breastmilk jaundice ... manifest only as jaundice ... and unconjugated
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... @AmyChung #Jaundice ... #Differential #Unconjugated
Inherited Colorectal Cancer (CRS) Syndromes
Adenomatous Polyposis Syndromes:
 • Familial Adenomatous Polyposis (FAP), Attenuated FAP (AFAP), MUTYH
Colorectal Cancer (CRS) Syndromes ... Adenomatous Polyposis Syndromes ... Urinary → Lynch Syndrome ... Peutz-Jeghers Syndrome ... #diagnosis #management
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Failure - Elevated conjugated ... and unconjugated ... the hepatorenal syndrome
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Reticulocyte Count ↑ - Unconjugated