30 results
management hematology differential oncology disease syndrome anemia cold infectiousdiseases table autoimmune classification cppd hemolytic hemophagocytic hiv hlh hodgkins infections lymphohistiocytosis
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Clinical triad: Fever ... Coxsackie, CMV, EBV ... Prunelle Getten #AdultOnset ... #management #treatment ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
: High spiking fever ... , CRP, AST+ALT, ... BrighamChiefs #AdultOnset ... Disease #AOSD #rheumatology ... #treatment
Warm vs Cold Autoimmune Hemolytic Anemia Warm Autoimmune Hemolytic Anemia: • Mechanism: IgG and Complement-mediated • Etiology:
Spherocytes • Treatment ... Mycoplasma, HIV, EBV ... transient hemolysis • Treatment ... Hemolytic #Anemia #hematology ... #diagnosis #comparison
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
explain symptoms • Fever ... : 33% • Treatment ... pulmonary edema) • Fever ... : No • Treatment ... #diagnosis #comparison
Fever vs Hyperthermia Fever: • Regulated in the hypothalamic thermoregulatory center • "Set point" raised by prostaglandin
Fever vs Hyperthermia ... Fever: • Regulated ... can cause harm as ... #Hyperthermia #comparison ... #diagnosis #management
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Non-Hodgkin's Lymphoma - Comparison ... - Pel-Ebstein fever ... body, but can also ... Differential Diagnosis ... #oncology #diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- 80% have fever ... organ damage • Treatment ... Low calcium • Treatment ... #diagnosis #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Auto-amplification loop Diagnosis ... • Clinical: fever ... Unknown cause Treatment ... #management #treatment ... #summary #rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... to repair DNA, as ... aplastic anemia Treatment ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
the disease is also ... following: • Fever ... • Bicytopenia Treatment ... #management #treatment ... #hematology
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